Primary Identifier | MGI:3712925 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Akap10 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A gene trap vector was inserted into the locus after exon 12. This insertion truncated the protein C terminus and eliminated the last 51 amino acids that include its PKA-binding domain. Immunoblot of cardiac tissue from mutants confirmed the absence of protein. |