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Publication : Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88.

First Author  Gillette-Ferguson I Year  2006
Journal  Infect Immun Volume  74
Issue  4 Pages  2442-5
PubMed ID  16552075 Mgi Jnum  J:107410
Mgi Id  MGI:3621098 Doi  10.1128/IAI.74.4.2442-2445.2006
Citation  Gillette-Ferguson I, et al. (2006) Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88. Infect Immun 74(4):2442-5
abstractText  Endosymbiotic Wolbachia bacteria that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role in the pathogenesis of river blindness. The current study demonstrates that corneal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dependent on expression of myeloid differentiation factor 88.
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