First Author | Gröbner S | Year | 2007 |
Journal | Infect Immun | Volume | 75 |
Issue | 1 | Pages | 512-7 |
PubMed ID | 17074859 | Mgi Jnum | J:116649 |
Mgi Id | MGI:3694616 | Doi | 10.1128/IAI.00756-06 |
Citation | Grobner S, et al. (2007) Absence of Toll-like receptor 4 signaling results in delayed Yersinia enterocolitica YopP-induced cell death of dendritic cells. Infect Immun 75(1):512-7 |
abstractText | In an initial period (< or =4 h) Toll-like receptor 4 (TLR4) signaling is required for Yersinia enterocolitica YopP-induced dendritic cell (DC) death. Later (>4 h), DC die independent of TLR4 signaling. In TLR4-deficient DC caspase 8 cleavage is delayed, indicating that TLR4 signaling accelerates caspase 8 activation, leading to DC death. |