Primary Identifier | MGI:2386203 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Oxt |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1 was replaced with a PGK-Hprt cassette via homologous recombination. The targeted deletion was confirmed in homozygous mutant animals by Southern blot analysis. In situ hybridization of brain sections verified the absence of gene expression in homozygous mutants. |