| Primary Identifier | MGI:5433359 | Allele Type | Targeted |
| Gene | Gja10 | Transmission | Germline |
| Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Homologous recombination replaced most of exon 2 with an FRT-flanked sequence encoding an HBEGF/EGFP (DTR/EGFP) fusion protein followed by cre recombinase with a nuclear localization signal. A PGK-neo selection cassette was inserted into intron 2. The diphtheria toxin receptor (HBEGF or DTR) is expressed from the Gja10 promoter and can be removed by flp-mediated recombination, leaving cre recombinase under control of the promoter. |
