Primary Identifier | MGI:104871 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 19046 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein serine/threonine phosphatase activity. Involved in circadian regulation of gene expression and entrainment of circadian clock by photoperiod. Located in cytoplasm. Is expressed in cornea; lens epithelium; lens fiber; limb; and retina. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 2. Orthologous to human PPP1CB (protein phosphatase 1 catalytic subunit beta). PHENOTYPE: Homozygous mutation of this gene results in lethality before weaning. [provided by MGI curators] |