Primary Identifier | MGI:1934582 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 80901 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables C-X-C chemokine binding activity and C-X-C chemokine receptor activity. Acts upstream of or within chemokine-mediated signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human CXCR6 (C-X-C motif chemokine receptor 6). PHENOTYPE: A small percentage of mice that are heterozygous or homozygous for a knock-out allele develop medulloblastomas in the cerebellum after 12 months of age. [provided by MGI curators] |