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Allele : Nkx2-5<tm1.2Mwc> NK2 homeobox 5; targeted mutation 1.2, Mauro W Costa

Primary Identifier  MGI:5788099 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nkx2-5
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted a loxP site upstream of exon 1 and an FRT-flanked neomycin selection cassette and loxP site in the 3' UTR in exon 2. Subsequent flp-mediated recombination removed the neo cassette and cre-mediated recombination deleted exon 1 and most of exon 2, leaving the 3' end of the 3' UTR.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nkx2-5delta,
  • Nkx2-5delta
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories