Primary Identifier | MGI:5788099 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nkx2-5 |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct inserted a loxP site upstream of exon 1 and an FRT-flanked neomycin selection cassette and loxP site in the 3' UTR in exon 2. Subsequent flp-mediated recombination removed the neo cassette and cre-mediated recombination deleted exon 1 and most of exon 2, leaving the 3' end of the 3' UTR. |