| Primary Identifier | MGI:7432724 | Allele Type | Other |
| Attribute String | Humanized sequence, Inserted expressed sequence, Null/knockout | Gene | Is(SYNGAP1-ZBTB9)1Bpro |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The targeting vector contains from 5' to 3' a loxP site, an FRT-flanked neomycin cassette, a human genomic DNA 37.5kb BAC encoding SYNGAP1 and the adjacent ZBTB9 (ENSMUST00000194598.6) genes, an F3-flanked hygromycin, followed by a second loxP site is used to replace the entire genomic region of the Syngap1 and up to the STOP codon of the Zbtb9 gene. The insertion results in a knock-out of the mouse Syngap1 and Zbtb9 genes. Flp-mediated recombination removed the neo and hygro cassettes. |
