| First Author | Foguet M | Year | 1992 |
| Journal | Neuroreport | Volume | 3 |
| Issue | 4 | Pages | 345-8 |
| PubMed ID | 1381232 | Mgi Jnum | J:40570 |
| Mgi Id | MGI:707918 | Doi | 10.1097/00001756-199204000-00014 |
| Citation | Foguet M, et al. (1992) Structure of the mouse 5-HT1C, 5-HT2 and stomach fundus serotonin receptor genes. Neuroreport 3(4):345-8 |
| abstractText | By analysis of the mouse 5-HT1C receptor gene we found that its coding region contains three introns. We next isolated cDNA and genomic clones for the closely related 5-HT2 receptor using a probe derived from the 5-HT1C receptor sequence. This probe also hybridized to an additional gene, called SRL (Serotonin Receptor Like). We have evidence demonstrating that it encodes the stomach fundus 5-HT receptor. Two introns are present within the coding regions of the mouse 5-HT2 receptor gene and the SRL gene at positions which correspond to those of introns in the 5-HT1C receptor gene. This intron distribution is unique and distinguishes these receptors from other members of the family of receptors coupled to G-proteins. |
