| Primary Identifier | MGI:6512847 | Allele Type | Targeted |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Hprt1 |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting construct is created using bacterial artificial chromosome RP11-1145H1, carrying a 170 kb insert from human chromosome 17. The BAC includes the entire GRN coding sequence (8 kb) plus approximately 8 kb of upstream sequence. The 35 kb construct including Hprt homologous recombination targeting arms was inserted into the Hprt locus. |
