Primary Identifier | MGI:6194942 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Pdgfc |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Based on NCBI transcript NM_019971_2, nucleotide substitutions were made that altered the following codons: K242T, K246R and R299S mutations have been introduced into exon 5, and K318R, N342S and A343T mutations have been introduced into exon 6. These mutations alter the mouse sequences to mimic the human amino acid sequence. |