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Protein Coding Gene : Gsta4 glutathione S-transferase, alpha 4

Primary Identifier  MGI:1309515 Organism  Mus musculus
Chromosome  9 NCBI Gene Number  14860
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 5.4.0)

Predicted to enable glutathione transferase activity; organic cyclic compound binding activity; and toxic substance binding activity. Predicted to be involved in glutathione metabolic process and xenobiotic metabolic process. Predicted to be located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ.
PHENOTYPE: Mice homozygous for disruptions in this gene display increased sensitivity to oxidative stress, increased alanine and aspartate transaminase levels, increased susceptibility to bacterial infection, reduced litter size, and impaired glucose tolerance. [provided by MGI curators]
  • synonyms:
  • Gsta4,
  • mGsta4,
  • GST 5.7,
  • glutathione S-transferase, alpha 4

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

1 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

32 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications