| Primary Identifier | IPR034393 | Type | Family |
| Short Name | TatSF1-like |
| description | Tat-SF1 (HIV Tat-specific factor 1) interacts with components of both the transcription and splicing machineries []. It has been shown to be a cofactor for human immunodeficiency virus-type 1 (HIV-1) Tat, which stimulates transcription elongation of HIV-1 through a series of events termed Tat transactivation [, ]. It contains two RNA recognition motifs (RRMs) and a highly acidic carboxyl-terminal half. This entry also includes Cus2, a yeast homologue of human Tat-SF1. Cus2 interacts with U2 snRNA and Prp11, a subunit of the conserved splicing factor SF3a []. Like Tat-SF1, Cus2 contains two RRMs. |
