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Protein Domain : Tyrosine aminotransferase ubiquitination region

Primary Identifier  IPR011715 Type  Domain
Short Name  Tyr_aminoTrfase_ubiquitination
description  This region contains a probable site of ubiquitination that ensures rapid degradation of tyrosine aminotransferase in rats. The half life of the enzyme in vivois about 2-4 hours. The enzyme contains at least 2 phosphorylation sites including CAPK at Ser29 and, at the other end of the protein, a casein kinase II site at S*QEECDK. This region of TAT is probably primarily related to regulatory events. Most other transaminases are much more stable and are not phosphorylated.

0 Child Features

0 Parent Features

3 Protein Domain Regions