| Type | caution | Description | Although related to variant histone H2AB1 in human (AC P0C5Y9), it is unclear whether human and mouse H2AB1 proteins are involved in similar processes. In mouse, variant histone H2AB1 is specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells during spermatogenesis (PubMed:28366643). It is however unclear whether human protein, which participates in mRNA processing and is associated with active transcription, is also involved in nucleosomes to protamine replacement. |
