| Primary Identifier | MGI:2685080 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 633979 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Predicted to enable adenylate kinase activity and nucleoside diphosphate kinase activity. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in brain; lung; and rib. Used to study normal pressure hydrocephalus. Human ortholog(s) of this gene implicated in spermatogenic failure 89. Orthologous to human AK9 (adenylate kinase 9). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility associated with asthenozoospermia. Homozygosity for a certain KO allele affects cilia motility and leads to male infertility and hydrocephalus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
