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Allele : Ighd<em1Smoc> immunoglobulin heavy constant delta; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Primary Identifier  MGI:7290369 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ighd
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1-6 of Ighm and exon 1-5 of Ighd gene was deleted to generate Ighm and Ighd knockout mice. Homozygous mutant mice lack mature B cells. It may be useful as a model for B cell immunodeficiency found in humans.
  • mutations:
  • Intragenic deletion
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