Primary Identifier | MGI:7657694 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Lrp1 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP-flanked PGK-neomycin selection cassette was inserted 240 bp upstream of the transcription initiation site, and a third loxP site was inserted 3' to exon 1 in intron 2. Cre-recombinase removed the PGK-neomycin selection cassette leaving the exon 1 flanked by loxP sites. |