Primary Identifier | MGI:1328306 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 18393 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables DNA replication origin binding activity. Predicted to be involved in DNA replication initiation. Predicted to act upstream of or within DNA replication. Part of heterochromatin; inner kinetochore; and nuclear origin of replication recognition complex. Is expressed in several structures, including 1st branchial arch maxillary component; brain; genitourinary system; sensory organ; and spleen. Orthologous to human ORC2 (origin recognition complex subunit 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality prior to organogenesis. [provided by MGI curators] |