| Primary Identifier | MGI:4821798 | Allele Type | Chemically induced (other) |
| Gene | Tpi1 | Inheritance Mode | Recessive |
| Strain of Origin | (101/El x C3H/El)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Triethylenemelamine mutagenesis induced an A to G transition at position 149 of exon 2 (GenBank/EMBL accession number NM009415) that results in the amino acid substitution of glycine for aspartic acid at position 49 (D49G). Triosephosphate isomerase activity in the blood, lung, spleen, heart, liver, kidney, and brain is reduced in heterozygotes and homozygotes. |
