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Allele : Hprt1<tm348a(Ple265-icre/ERT2)Ems> hypoxanthine phosphoribosyltransferase 1; targeted mutation 348a, Elizabeth M Simpson

Primary Identifier  MGI:5532501 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Hprt1
Transmission  Germline Strain of Origin  B6N.Cg-A<w-J> Hprt1<b-m3>
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false Project Collection  EUCOMMTOOLS
molecularNote  The transgene was designed with an HS4 insulator region, the 986 bp Ple265 minipromoter (based on PCP2-B; derived from a portion of the endogenous promoter (Prom 1 ONLY) from the human purkinje cell protein 2 (PCP2) locus), a chimeric intron cassette, the iCre/ERT2 fusion gene (with F3-frt sites flanking the ERT2 sequences), the mut6-WPRE element, an SV40 early polyA signal, an additional HS4 insulator region, a human HPRT complementary sequence (containing exon 1, intron 1, exon 2, and part of intron 2), a mouse 3' Hprt homology arm, an I-Sce linearization cut site, and a mouse 5' Hprt homology arm.
  • mutations:
  • Insertion
  • synonyms:
  • Ple265-icre/frt/ERT2/frt;mEMS5991,
  • PCP2-creERT2,
  • PCP2-creERT2,
  • Ple265-icre/frt/ERT2/frt;mEMS5991
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

1 Driven By

Trail: Allele

4 Publication categories

Trail: Allele