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Allele : Hprt1<tm351a(Ple198-icre/ERT2)Ems> hypoxanthine phosphoribosyltransferase 1; targeted mutation 351a, Elizabeth M Simpson

Primary Identifier  MGI:5532519 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Hprt1
Transmission  Germline Strain of Origin  B6N.Cg-A<w-J> Hprt1<b-m3>
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false Project Collection  EUCOMMTOOLS
molecularNote  The transgene was designed with an HS4 insulator region, the 2826 bp Ple198 minipromoter (SLC6A4-D; derived from a portion of the endogenous promoter and two upstream putative regulatory elements from the human solute carrier family 6 member 4 (SLC6A4) locus), a chimeric intron cassette, the iCre/ERT2 fusion gene (with F3-frt sites flanking the ERT2 sequences), the mut6-WPRE element, an SV40 early polyA signal, an additional HS4 insulator region, a human HPRT complementary sequence (containing exon 1, intron 1, exon 2, and part of intron 2), a mouse 3' Hprt homology arm, an I-Sce linearization cut site, and a mouse 5' Hprt homology arm.
  • mutations:
  • Insertion
  • synonyms:
  • SLC6A4-creERT2,
  • Ple198-icre/frt/ERT2/frt;mEMS6044,
  • SLC6A4-creERT2,
  • Ple198-icre/frt/ERT2/frt;mEMS6044
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

1 Driven By

Trail: Allele

4 Publication categories

Trail: Allele