| Type | MGI:General | Description | in vitro, purified mutant B cells display reduced up-regulation of various surface molecules, including CD23, CD54, CD80, CD86 and Fas, in response to stimulation with agonistic anti-CD40 mAb proliferative responses of mutant purified B cells to anti-CD40, CD40 ligand, and anti-CD40 plus anti-IgM are significantly reduced relative to those of wild-type B cells; addition of IL-4 partially restores the response |
