Primary Identifier | MGI:5447369 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Trp53cor1 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The promoter region and first exon, which includes the Trp53 response element (p53RE), are flanked by loxP sites and an FRT-Neo-FRT drug selection cassette is placed downstream of exon 1, just inside the floxed region. Flp-mediated recombination removed the neo cassette. |