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Comment :

Type  MGI:General Description  lenses appear normal at P8, however by P21, lens fiber cells show variable degrees of degeneration, with small vacuoles appearing in the equatorial epithelial cells and superficial cortical fiber cells by 6 weeks of age, all lenses exhibit abnormalities comprising of large vacuoles in cortical fiber cells and swollen nucleated fiber cells (bladder cells) with protein-filled lacunae the fiber cell migration and elongation patter is defective at the equatorial region