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Protein Coding Gene : Cldn7 claudin 7

Primary Identifier  MGI:1859285 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  53624
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable cell adhesion molecule binding activity; identical protein binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including bicellular tight junction assembly; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; and negative regulation of protein-containing complex assembly. Located in several cellular components, including apicolateral plasma membrane; basolateral plasma membrane; and lateral plasma membrane. Is expressed in several structures, including alimentary system; early conceptus; olfactory epithelium; respiratory system; and urinary system. Orthologous to human CLDN7 (claudin 7).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body size, weight, and length; abnormal potassium, chloride, and sodium ion excretion; chronic dehydration; and postnatal lethality by P12. [provided by MGI curators]
  • synonyms:
  • claudin 7,
  • Cldn7

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For