Primary Identifier | MGI:2137354 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 94090 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable several functions, including SNARE binding activity; protein homodimerization activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of SNARE complex assembly; negative regulation of calcium ion-dependent exocytosis; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within synaptic vesicle exocytosis. Located in cytoplasm and dendrite. Is expressed in several structures, including alimentary system; limb; nervous system; sensory organ; and urinary system. Orthologous to human TRIM9 (tripartite motif containing 9). PHENOTYPE: Mice homozygous for a null mutation display increased axonal branching and increased corpus callosum thickness. [provided by MGI curators] |