Primary Identifier | MGI:7411151 | Allele Type | Transposon induced |
Attribute String | Conditional ready, Modified regulatory region, Reporter | Gene | Del(15Rr316124-Rr313939)2Fsp |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.192339Fsp at chr15:63332129-63332130 (GRCm39) and Tn(sb-SBlac)15.179039Fsp at chr15:63590844-63590845 deleted approximately 259 kb and leaves one intact copy of the transposon cassette (in forward orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. The deleted sequence is part of the Myc topologically associating domain (TAD) and contains Myc enhancers Rr316124, Rr313933, Rr331, Rr307328, Rr332, Rr307330, Rr333 and Rr313939. |