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Publication : Reactive oxygen species in cancer: a dance with the devil.

First Author  Schumacker PT Year  2015
Journal  Cancer Cell Volume  27
Issue  2 Pages  156-7
PubMed ID  25670075 Mgi Jnum  J:219950
Mgi Id  MGI:5630015 Doi  10.1016/j.ccell.2015.01.007
Citation  Schumacker PT (2015) Reactive oxygen species in cancer: a dance with the devil. Cancer Cell 27(2):156-7
abstractText  Reactive oxygen species (ROS) can initiate cancer, but oxidant generation in tumors leaves them vulnerable to further stresses. In this issue of Cancer Cell, Harris and colleagues show that augmenting oxidant stress in normal cells limits tumor initiation and progression. Hence, strategic targeting of antioxidant systems may undermine survival of new tumor cells.
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