| First Author | Ruble DM | Year | 1998 |
| Journal | Gene | Volume | 218 |
| Issue | 1-2 | Pages | 95-101 |
| PubMed ID | 9751807 | Mgi Jnum | J:50190 |
| Mgi Id | MGI:1290011 | Doi | 10.1016/s0378-1119(98)00383-7 |
| Citation | Ruble DM, et al. (1998) Molecular cloning and characterization of a highly conserved chicken cellular nucleic acid binding protein cDNA. Gene 218(1-2):95-101 |
| abstractText | A chicken cellular nucleic acid binding protein (cCNBP) cDNA was isolated from a chicken Con-A-stimulated immune cell library by differential screening. cCNBP is a Cys/Cys-His/Cys zinc finger DNA binding protein of unknown function. The chicken CNBP nucleotide and deduced amino acid sequence showed extraordinary sequence conservation (between 81-98% similarities) when compared to human, mouse and rat CNBP. The CNBP gene was shown to be a single copy and to cross- hybridize to human and mouse genomic DNA. A Northern blot analysis revealed cCNBP to be a constitutively expressed gene in a wide variety of tissues and to be differentially expressed in cultured chicken spleen and bursal cells after mitogen stimulation. |
