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GO Term : SAGA complex [GO:0000124] Gene Ontology

Namespace  cellular_component Obsolete  false
description  A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).
  • synonyms:
  • PCAF complex,
  • PCAF histone acetylase-associated complex,
  • STAGA coactivator complex,
  • STAGA complex,
  • GO:0000125,
  • GO:0030914,
  • Spt-Ada-Gcn5-acetyltransferase complex,
  • SPT3-TAF9-PCAF acetylase complex,
  • SPT3-TAF9-GCN5 acetylase complex
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Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents