Primary Identifier | MGI:1330300 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 226419 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in erythrocyte differentiation; negative regulation of DNA damage response, signal transduction by p53 class mediator; and negative regulation of apoptotic process. Predicted to be located in several cellular components, including cytoplasmic stress granule; nuclear speck; and pericentriolar material. Predicted to be active in cytoplasm; cytoskeleton; and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; musculature; and nasal cavity epithelium. Orthologous to human DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3). PHENOTYPE: Mice homozygous for a null allele exhibit increased erythropoiesis in response to chemically-induced anemia. [provided by MGI curators] |