Primary Identifier | MGI:1195269 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 20521 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables urate transmembrane transporter activity. Acts upstream of or within urate transport. Located in brush border membrane. Is expressed in central nervous system; dorsal root ganglion; male reproductive gland or organ; metanephros; and retina layer. Orthologous to human SLC22A12 (solute carrier family 22 member 12). PHENOTYPE: Mice homozygous for a null allele exhibit increased urinary urate levels and altered urine and plasma metabolite composition. [provided by MGI curators] |