Primary Identifier | MGI:2176180 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(CMV-cre)1Cgn |
Strain of Origin | BALB/cJ | Is Recombinase | true |
Is Wild Type | false |
description | Homozygous transgenic mice are viable and fertile. The transgene appears to be X-linked since transgene transmission through males is restricted to female offspring. In transgenic mice, in conjunction with a transgene carrying a loxP-flanked gene, deletion of the loxP-flanked gene occurs in all tissues including germ cells. |
molecularNote | This transgene expresses Cre recombinase under the control of a human cytomegalovirus (CMV) promoter, active in most cells and tissues. |