| First Author | Maher F | Year | 1992 |
| Journal | Biochem Biophys Res Commun | Volume | 182 |
| Issue | 2 | Pages | 703-11 |
| PubMed ID | 1734877 | Mgi Jnum | J:1658 |
| Mgi Id | MGI:50185 | Doi | 10.1016/0006-291x(92)91789-s |
| Citation | Maher F, et al. (1992) Expression of mouse-GLUT3 and human-GLUT3 glucose transporter proteins in brain. Biochem Biophys Res Commun 182(2):703-11 |
| abstractText | Polyclonal anti-peptide antisera were raised to the C-terminal sequence of mouse- and human-GLUT3 glucose transporter isoforms. GLUT3 protein and mRNA expression were investigated by Western blot and Northern blot assays, in a range of tissues and cell lines. Mouse-GLUT3 protein was detected only in rat brain, where it was present in most regions except adenohypophysis and pineal gland. Mouse-GLUT3 was also detected in primary cultured rat cerebellar neurons and the neuronal cell lines PC12 and NG108-15, but not in cultured astroglia. Human-GLUT3 protein was detected in CHO cells transfected with the human-GLUT3 cDNA and in human brain, but not in human placenta or fat. The expression of GLUT3 in rat brain and neurons indicates it is a major neuronal glucose transporter. |
