Primary Identifier | MGI:2676817 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 387150 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to forskolin; long-term synaptic potentiation; and regulation of neuron maturation. Located in postsynaptic density. Is expressed in cerebellum; embryo; lung; and telencephalon. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Orthologous to human MIR132 (microRNA 132). PHENOTYPE: Mice homozygous for an allele lacking both Mir212 and Mir132 exhibit disrupted cortical synaptic transmission and plasticity. Mice homozygous for another knock-out allele exhibit abnormal mammary gland development (see Mirc19). [provided by MGI curators] |