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Allele : Gt(ROSA)26Sor<tm1(cre/ERT2)Thl> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Thomas Ludwig
Primary Identifier  MGI:3701992 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  DNA sequence encoding a fusion protein comprised of cre recombinase and a mutated ligand binding domain of Esr1 (ERT2) was inserted at the endogenous locus via homologous recombination. Activation of cre recombinase activity is dependent on the administration of 4-OH-tamoxifen.
  • mutations:
  • Insertion
  • synonyms:
  • ERCre,
  • Gt(ROSA)26Sor<tm1(cre/ESR1)Thl>,
  • ROSA26Cre-ERT2,
  • Gt(ROSA)26Sor<tm1(cre/ESR1)Thl>,
  • ERCre,
  • Gt(ROSA)26Sor-CreER,
  • Gt(ROSA)26Sor-CreER,
  • ROSA26Cre-ERT2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

Trail: Allele

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Trail: Allele




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