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Allele : Ryr1<em2Jjd> ryanodine receptor 1, skeletal muscle; endonuclease-mediated mutation 2, James Dowling

Primary Identifier  MGI:6437883 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ryr1
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 endonuclease-mediated genome editing introduced an indel comprised of a 16 bp (Chr7:29013738 to 29013752) deletion in exon 96 of the gene. Sequencing N1 pups revealed the repair template was not incorporated into this allele, which resulted from non-homologous end-joining repair of the double strand break.
  • mutations:
  • Deletion
  • synonyms:
  • Ryr1<Indel>,
  • Ryr1<Indel>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele