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Allele : Gt(ROSA)26Sor<tm1.2(Cyp1a1,Thy1)Stck> gene trap ROSA 26, Philippe Soriano; targeted mutation 1.2, Brigitta Stockinger
Primary Identifier  MGI:7311753 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A minigene composed of the coding sequences of mouse Cyp1a1 and rat Thy1 connected by a 2A sequence followed by the Woodchuck hepatitis virus derived regulatory element and a bovine growth hormone polyadenylation site was inserted into the locus. In addition a cassette containing an FRT-flanked neomycin-resistance gene and loxP-flanked transcriptional stop elements were inserted upstream of the minigene. Flp-mediated recombination removed the neomycin resistance gene, leaving the floxed STOP cassette. Cre-mediated recombination removed the STOP cassette.
  • mutations:
  • Insertion
  • synonyms:
  • R26<Cyp1a1>,
  • R26<Cyp1a1>
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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