| Primary Identifier | MGI:3693832 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 14339 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in several processes, including early endosome to late endosome transport; protein K63-linked ubiquitination; and protein localization to perinuclear region of cytoplasm. Predicted to act upstream of or within positive regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be part of FHF complex and HOPS complex. Predicted to be active in nucleus. Is expressed in several structures, including ganglia; genitourinary system; hemolymphoid system gland; lung; and skin. Orthologous to human AKTIP (AKT interacting protein). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit impaired growth, skeletal and skin defects, abnormal heart tissue, and sterility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
