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Protein Coding Gene : Man2a2 mannosidase 2, alpha 2
Primary Identifier  MGI:2150656 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  140481
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables hydrolase activity, hydrolyzing N-glycosyl compounds and mannosidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Is expressed in olfactory epithelium; retina outer nuclear layer; skeletal muscle; and vomeronasal organ. Orthologous to human MAN2A2 (mannosidase alpha class 2A member 2).
PHENOTYPE: Homozygous null males are infertile due to a defect during spermatogenesis involving the premature release of germ cells from the seminiferous tubules into the epididymis. [provided by MGI curators]
  • synonyms:
  • MGI:2141983,
  • 4931438M07Rik,
  • MGI:1920604,
  • RIKEN cDNA 4931438M07 gene,
  • 1700052O22Rik,
  • MGI:2444118,
  • expressed sequence AI480988,
  • RIKEN cDNA 1700052O22 gene,
  • Man2a2,
  • mannosidase 2, alpha 2,
  • AI480988,
  • MX,
  • alpha mannosidase IIx
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Features --> Cross References

Genome

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3 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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