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Allele : Notch1<em1Rsh> notch 1; endonuclease-mediated mutation 1, Robert S Haltiwanger
Primary Identifier  MGI:7511610 Allele Type  Endonuclease-mediated
Gene  Notch1 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISRP/Cas9 technology generated an ACC to GTG change at nt19507–19510 resulting in a threonine to valine substitution at amino acid 232 (p.T232V) in exon 4, resulting in a hypermorphic allele.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Notch1<6f>,
  • Notch1<T232V>,
  • Notch1<T232V>,
  • Notch1<6f>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele




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