Primary Identifier | MGI:6115592 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Dppa3 |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR targeting produced a ACGG to GGCC nucleotide substitution that results in the amino acid substitution of alanine for arginine at position 60 (R60A). This mutation abolishes cytoplasmic cleavage. |