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Allele : Dppa3<em1Dean> developmental pluripotency-associated 3; endonuclease-mediated mutation 1, Jurrien Dean

Primary Identifier  MGI:6115592 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Dppa3
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR targeting produced a ACGG to GGCC nucleotide substitution that results in the amino acid substitution of alanine for arginine at position 60 (R60A). This mutation abolishes cytoplasmic cleavage.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Dppa3<R60A>,
  • Dppa3<R60A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele