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Allele : Pou2f2<tm1Lmc> POU domain, class 2, transcription factor 2; targeted mutation 1, Lynn M Corcoran

Primary Identifier  MGI:3037094 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pou2f2
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a translational stop codon at the end of the POU homeodomain encoding exon by homologous recombination results a truncated protein. All sequences C-terminal to the DNA-binding domain are removed from proteins translated from this allele. Western blots demonstrated that this truncated protein is produced and stable in vitro.
  • mutations:
  • Insertion
  • synonyms:
  • Oct2<deltaC>,
  • Oct2<deltaC>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele