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Protein Coding Gene : Sun1 Sad1 and UNC84 domain containing 1

Primary Identifier  MGI:1924303 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  77053
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 5.4.0)

Enables lamin binding activity. Involved in centrosome localization; meiotic attachment of telomere to nuclear envelope; and nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration. Acts upstream of or within homologous chromosome pairing at meiosis. Located in chromosome, telomeric region; cytoplasm; and nuclear inner membrane. Is expressed in intercostal muscle; spermatocyte; and spermatozoon. Orthologous to human SUN1 (Sad1 and UNC84 domain containing 1).
PHENOTYPE: Mice homozygous for a null allele exhibit sterility due to arrested meiosis, hearing loss associated with outer hair cell degeneration, abnormal cerebellum development, ataxia, impaired motor coordination, and abnormal Purkinje cell migration. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 4632417G13 gene,
  • 5730434D03Rik,
  • mKIAA0810,
  • MGI:1922034,
  • unc-84 homolog A (C. elegans),
  • Sun1,
  • 4632417G13Rik,
  • Sad1 and UNC84 domain containing 1,
  • Unc84a,
  • RIKEN cDNA 5730434D03 gene

Features --> Cross References


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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features


Gene --> Proteins


Mouse features --> Functions (GO terms)


Genes --> Homologs


0 Pathways

324 Targeted By

Gene --> Protein-Protein Interactions


Gene --> Expression annotations


Genes/Features --> Phenotypes (MP terms)


Mouse features --> Human diseases


Mouse features --> Publications



0 Driver For