Primary Identifier | MGI:1857160 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Edn3 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129S7/SvEvBrd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A neomycin cassette was inserted into the middle of exon 2, deleting the mature Edn3-encoding portion of the exon. No mature Edn3 protein was detected by EIA of kidney, brain, or intestine from homozygous mutant mice. |