| First Author | McCormick F | Year | 2018 |
| Journal | Cancer Cell | Volume | 33 |
| Issue | 2 | Pages | 158-159 |
| PubMed ID | 29438690 | Mgi Jnum | J:257778 |
| Mgi Id | MGI:6119317 | Doi | 10.1016/j.ccell.2018.01.017 |
| Citation | McCormick F (2018) c-Raf in KRas Mutant Cancers: A Moving Target. Cancer Cell 33(2):158-159 |
| abstractText | Therapies for KRas cancers remain a major clinical need. In the current issue of Cancer Cell, Sanclemente and coworkers in Mariano Barbacid''s group validate c-Raf as a prime target for these cancers. c-Raf ablation caused regression of advanced KRas(G12V)/Trp53 tumors, without obvious systemic toxicity and without affecting MAPK signaling. |
