| Primary Identifier | MGI:5433291 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Crx-cre)764Gla |
| Strain of Origin | (C57BL/6J x SJL/J)F2 or (B6;129-Gt(ROSA)26Sor<tm1Sho>/J x (C57BL/6 x SJL)F1) | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | A targeting construct containing a cre-FRT-amp-FRT cassette with an SV40 polyA sequence was used to target the Crx gene in BAC clone RP23-81H17 by recombineering methods in bacteria. The cassette was inserted after the ATG initiation codon in exon 2. The amp selection cassette was deleted in targeted clones. The purified BAC-cre construct was injected into fertilized oocytes. More than 3 lines were generated and line 60 was more extensively characterized. |
