| First Author | Andrews SJ | Year | 1983 |
| Journal | Biochem Genet | Volume | 21 |
| Issue | 7-8 | Pages | 809-17 |
| PubMed ID | 6626150 | Mgi Jnum | J:7208 |
| Mgi Id | MGI:55679 | Doi | 10.1007/BF00498928 |
| Citation | Andrews SJ, et al. (1983) Linkage analyses and biochemical genetics of sorbitol dehydrogenase-1 (Sdh-1) in the mouse. Biochem Genet 21(7-8):809-17 |
| abstractText | Electrophoretic variation of sorbitol dehydrogenase has been found in Mus musculus; the SDH-1 A phenotype migrates further toward the cathode under the conditions used than the SDH-1B phenotype. Mice with the SDH-1B phenotype have enzyme activity reduced to 25% of that found in mice with the SDH-1A phenotype, but no differences in heat stability, pH profile, or Km for fructose were found. The gene Sdh-1 is inherited as an autosomal condominant located on chromosome 2, and the gene order obtained, with genetic distance calculated as percentage recombination +/- SE was Sdh-1--1.9 +/- 1.4--pa--16.4 +/- 3.6--a--3.9 +/- 1.9--bp. |
